近几年发表的主要学术论文(通讯或共同通讯作者)

　　1. Zhou Y, Huang X, Zhao T, Qiao M, Zhao X, Zhao M, Xu L, Zhao Y, Wu L, Wu K, Chen R, Fan M, Zhu L. Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice. Brain Behav Immun. 2017 Apr 20. pii: S0889-1591(17)30115-0. doi: 10.1016/j.bbi.2017.04.013.

　　2. Zhao M, Huang X, Cheng X, Lin X, Zhao T, Wu L, Yu X, Wu K, Fan M, Zhu L. Ketogenic diet improves the spatial memory impairment caused by exposure to hypobaric hypoxia through increased acetylation of histones in rats. PLoS One. 2017 Mar 29;12(3):e0174477

　　3. Li D, Zhang L, Xu L, Liu L, He Y, Zhang Y, Huang X, Zhao T, Wu L, Zhao Y, Wu K, Li H, Yu X, Zhao T, Gong S, Fan M, Zhu L. WIP1 phosphatase is a critical regulator of adipogenesis through dephosphorylating PPARγ serine 112. Cell Mol Life Sci. 2017 Feb 8. doi: 10.1007/s00018-016-2450-4

　　4. Zhao M, Huang X, Cheng X, Lin X, Zhao T, Wu L, Yu X, Wu K, Fan M, Zhu L. Ketogenic diet improves the spatial memory impairment caused by exposure to hypobaric hypoxia through increased acetylation of histones in rats. PLoS One. 2017 Mar 29;12(3):e0174477

　　5. Li D, Zhang L, Huang X, Liu L, He Y, Xu L, Zhang Y, Zhao T, Wu L, Zhao Y, Wu K, Wu Y, Fan M, Zhu L. WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation. Neurosci Bull. 2017 Jan 17. doi: 10.1007/s12264-016-0095-9.

　　6. Chen X, Zhao T, Huang X, Wu L, Wu K, Fan M, Zhu L. Intermittent hypoxia maintains glycemia in streptozotocin-induced diabetic rats. Cell Stress Chaperones. 2016 May;21(3):515-22. doi: 10.1007/s12192-016-0679-3.

　　7. Zhang K, Zhao T, Huang X, He Y, Zhou Y, Wu L, Wu K, Fan M, Zhu L. Dissolved oxygen concentration in the medium during cell culture: Defects and improvements. Cell Biol Int. 2016 Mar;40(3):354-60.

　　8. Zhang K, Zhou Y, Zhao T, Wu L, Huang X, Wu K, Xu L, Li D, Liu S, Zhao Y, Fan M, Zhu L. Reduced Cerebral Oxygen Content in the DG and SVZ In Situ Promotes Neurogenesis in the Adult Rat Brain In Vivo. PLoS One. 2015 Oct 14;10(10):e0140035.

　　9. Di Y, He YL, Zhao T, Huang X, Wu KW, Liu SH, Zhao YQ, Fan M, Wu LY, Zhu LL. Methylene Blue Reduces Acute Cerebral Ischemic Injury via the Induction of Mitophagy. Mol Med. 2015 May 19;21:420-9. doi: 10.2119/molmed.2015.00038.

　　10. Zhang JH, Di Y, Wu LY, He YL, Zhao T, Huang X, Ding XF, Wu KW, Fan M, Zhu LL. 5-HMF prevents against oxidative injury via APE/Ref-1. Free Radic Res. 2015 Jan;49(1):86-94.

　　11. He YL, Li MM, Wu LY, Zhao T, Di Y, Huang X, Ding XF, Wu KW, Fan M, Zhu LL. Enhanced hypoxia-inducible factor (HIF)-1α stability induced by 5-hydroxymethyl-2-furfural (5-HMF) contributes to protection against hypoxia. Mol Med. 2015 Feb 23;20:590-600.

　　12. Huang X, Zhou Y, Zhao T, Han X, Qiao M, Ding X, Li D, Wu L, Wu K, Zhu LL, Fan M. A method for establishing the high-altitude cerebral edema (HACE) model by acute hypobaric hypoxia in adult mice. J Neurosci Methods. 2015 Apr 30;245:178-81.

　　13. Zhang K, Zhao T, Huang X, Wu LY, Wu K, Zhu LL, Fan M. Notch1 mediates postnatal neurogenesis in hippocampus enhanced by intermittent hypoxia. Neurobiol Dis. 2014 Apr;64:66-78.

　　14. Huang X, Sun J, Rong W, Zhao T, Li DH, Ding X, Wu LY, Wu K, Schachner M, Xiao ZC, Zhu LL, Fan M. Loss of cell adhesion molecule CHL1 improves homeostatic adaptation and survival in hypoxic stress. Cell Death Dis. 2013 Aug 15;4:e768. doi: 10.1038/cddis.2013.284.

　　15. Fei Wang, Lei Xiong, Xin Huang, Tong Zhao, Li-ying Wu, hao-hui Liu,Xuefeng Ding, Shuhong Liu, Yan Wu, Yongqi Zhao, Kuiwu Wu, Ling-ling Zhu*, Ming Fan*, miR-210 directly suppresses BNIP3 expression to protect against the hypoxia-induced apoptosis of neural progenitor cells. Stem Cell Research, 2013,11：657–667

　　16. Ding XF, Zhao YQ, Fan WH, Wu LY, Huang X, Wang F, He YL, Liu SH, Wu Y, Zhao T, Wu Y, Zhu LL*, Fan M*，Gene transfer into the both sides of postnatal cerebral cortex using tweezer electrode. CNS Neurosci Ther. 2013 Mar;19(3):197-8.

　　17. Xiong L, Wang F, Huang X, Liu ZH, Zhao T, Wu LY, Wu K, Ding X, Liu S, Wu Y, Zhao Y, Zhu LL*, Fan M*, DNA demethylation regulates the expression of miR-210 in neural progenitor cells subjected to hypoxia. FEBS J, 2012. 279(23): p. 4318-26. I

　　18. Ding XF, Zhao YQ, Hu ZY, Lin K, Wang F, Liu SH, Wu Y, Wu LY, Zhao T, Huang X, Wu Y, Zhu LL*, Fan WH*, Fan M*.　Efficient gene transfer into neonatal mouse brain using electroporation.　Neurochem Res. 2012 Jul;37(7):1392-8.

　　19. Xin Huang, Jia Sun, Tong Zhao, Kui-Wu Wu, Kazutada Watanabe, Zhi-Cheng Xiao, Ling-Ling Zhu*, Ming Fan*, Loss of NB-3 Aggravates Cerebral Ischemia by Impairing Neuron Survival and Neurite Growth. Stroke. 2011, 42: 2910-2916.

　　20. Xin Huang, Ling-ling Zhu*, Tong Zhao, Li-ying Wu, Kui-wu Wu, Melitta Schachner, Zhi-Cheng Xiao, Ming Fan*. CHL1 negatively regulates the proliferation and neuronal differentiation of neural progenitor cells through activation of the ERK1/2MAPK pathway. Molecular and Cellular Neuroscience 2011; 46:296–307.

　　21. Liu ZH, Yang G, Zhao T, Cao GJ, Xiong L, Xia W, Huang X, Wu LY, Wu K, Fan M, Shao NS, Zhu LL*. Small ncRNA expression and regulation under hypoxia in neural progenitor cells. Cell Mol Neurobiol, 2011, 31:1–5

　　22. Ling-ling Zhu, Tong Zhao, Xin Huang，Li-ying Wu, Kui-wu Wu, Ming Fan*. Gene Expression Profiles and Metabolic Changes in Embryonic Progenitor Cells under Low Oxygen. Cell Reprogramming 2011，13:113-120